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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (whole mount)
Postnatal

3 matching records from 3 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
Top2a  topoisomerase (DNA) II alpha   (Synonyms: DNA Topoisomerase II alpha, Top-2)
Results  Reference
1J:241574 Hwang G, Sun F, O'Brien M, Eppig JJ, Handel MA, Jordan PW, SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes. Development. 2017 May 01;144(9):1648-1660
1J:282460 Rong Y, Ji SY, Zhu YZ, Wu YW, Shen L, Fan HY, ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation. Nucleic Acids Res. 2019 Dec 2;47(21):11387-11402
1J:344223 Zhang W, Zhang R, Wu L, Zhu C, Zhang C, Xu C, Zhao S, Liu X, Guo T, Lu Y, Gao Z, Yu X, Li L, Chen ZJ, Qin Y, Jiao X, NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance. Cell Rep. 2023 Dec 26;42(12):113531

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory